15+ DHC supplements for skin, immunity & overall health

If you're searching for a DHC supplement to improve your skin, immunity, or everyday wellness, you’re not alone. These Japanese-made wellness boosters have become a global favorite, especially among beauty enthusiasts in the US, UK, Canada, and Australia. Known for their high-quality ingredients and targeted results, DHC food supplements are designed to address modern health needs with simplicity and precision. At Japan With Love, we’ve curated the best DHC supplements to help you build a beauty-from-within routine that actually works.

If you’ve ever searched for beauty and wellness support straight from Japan, chances are you’ve come across a DHC supplement. Known for combining simplicity, science-backed formulas, and everyday convenience, DHC (Daigaku Honyaku Center) is Japan’s go-to brand for both skincare and nutritional supplements. Here are the top reasons why you should choose DHC supplements over other products in the market:

• Made in Japan with trusted quality: DHC (Daigaku Honyaku Center) is one of Japan’s most reputable health and beauty brands, trusted for over 50 years.
• Science-backed, minimalist formulas: Unlike many Western multivitamins, DHC food supplements use clean, targeted ingredients without unnecessary fillers or additives.
• Targeted health solutions: Each DHC supplement is designed for a specific purpose, such as skin elasticity, immunity, digestion, or brain clarity, so you only take what your body truly needs.
• Highly digestible & easy to take: Compact capsules and softgels make daily intake simple—no large pills, messy powders, or unpleasant aftertastes.
• Tailored for busy, modern lifestyles: Perfect for people with hectic schedules or nutrient gaps from imbalanced diets, especially popular among users in the US, UK, Canada, and Australia.
• Backed by over 100 million users worldwide: With a strong global following, DHC supplements have earned trust through visible results and long-term effectiveness.

DHC’s wide-ranging lineup can be overwhelming, so we’ve handpicked the top 15+ supplements for beauty and health in 2025.

1. DHC Collagen
2. DHC Vitamin C
3. DHC Vitamin B Mix
4. DHC Perfect Vegetables Premium
5. DHC Calcium & Magnesium
6. DHC Heme Iron
7. DHC Multivitamin
8. DHC Hatomugi Extract
9. DHC Blueberry Extract
10. DHC Plasmalogen for Brain Function
11. DHC Japanese Perfect Vegetables Premium
12. DHC Natural Vitamin E
13. DHC Vitamin D
14. DHC DHA Omega-3 fish oil
15. DHC Atsu Balance Supplement

A top-selling DHC supplement, among the top 10 collagen in Japan, DHC Collagen delivers around 2,050 mg of fish-derived collagen peptides per daily serving, along with Vitamins B1 and B2, ideal for supporting skin hydration, elasticity, and firmness. Collagen naturally declines with age, so this supplement helps replenish what we lose gradually. It’s compact, easy to swallow, and designed for daily routine. Studies suggest that 2.5–15 g of hydrolyzed collagen is generally safe and effective for skin and joints. While DHC Collagen is on the lower end of this spectrum, it's still beneficial for ongoing skin maintenance.

• Key ingredients: 2,050 mg collagen peptides, Vitamin B1, Vitamin B2
• Effect: Improves skin elasticity, firmness, and hydration
• Best for: Mature or dry skin, early signs of aging
• Who should avoid: Those with allergies to marine collagen or fish
• Combine with: DHC Vitamin C to support collagen synthesis

This powerhouse DHC supplement provides a solid 1,000 mg of Vitamin C daily in time-release capsules, along with 2 mg of Vitamin B2 to support absorption. This dosage is drastically higher than typical dietary intake, but it's still within safe limits (upper intake level is 2,000 mg/day). Users often report brighter skin, improved immunity, and reduced fatigue after continued use. Vitamin C also plays a crucial role in collagen production, making it a great pair with DHC Collagen (view more at DHC collagen review before and after).

• Key ingredients: 1,000 mg Vitamin C, 2 mg Vitamin B2
• Effect: Supports immune system, antioxidant defense, skin brightness
• Best for: Those with low immunity, uneven pigmented skin, or stress
• Who should avoid: People with kidney conditions or Vitamin C sensitivity
• Combine with: DHC Collagen or DHC Multivitamin

This convenient B-complex blend includes eight essential B vitamins, such as B1, B2, B6, B12, niacin, and folic acid, to support metabolism, brain function, stress response, and skin clarity (especially for hormonal or stress-related acne). While manufacturer details vary, DHC's B Mix is consistent with standard formulations that boost energy and tone.

• Key ingredients: B1, B2, B6, B12, niacin, folic acid
• Effect: Enhances energy, balances hormones, clarifies skin, elevates mood
• Best for: Stressed individuals, acne-prone or fatigued people
• Who should avoid: Those with sensitivity to B vitamins or already on high-dose B supplements
• Combine with: DHC Vitamin C or Hatomugi for skin-support synergy

A true DHC food supplement, this capsule captures the benefits of 32 Japanese vegetables, mushrooms, and herbs in one easy-to-take format. It's designed to support digestion, provide antioxidants, and fill nutritional gaps, especially useful for those with poor veggie intake or on-the-go lifestyles. While DHC doesn’t list quantities, Japanese vegetable extracts are known for nutrient density.

• Key ingredients: Kale, spinach, burdock root, carrots, shiitake mushrooms, and more
• Effect: Boosts antioxidant intake, supports gut health, improves nutrient balance
• Best for: People with low vegetable consumption, digestive issues, busy routines
• Who should avoid: Those with allergies to any ingredients
• Combine with: DHC Multivitamin or probiotics

This targeted mineral formula combines calcium carbonate and magnesium oxide to support bone density, muscle health, and relaxation, ideal for older adults, athletes, or anyone needing better sleep quality through muscle recovery. The capsule’s gentle formulation is suitable for those with sensitive digestion.

• Key ingredients: Calcium carbonate, magnesium oxide
• Effect: Enhances bone and muscle health; eases cramps; supports rest
• Best for: Aging individuals, active adults, or PMS sufferers
• Who should avoid: People with hypercalcemia or a history of kidney stones
• Combine with: DHC Vitamin D to improve calcium absorption

DHC Heme Iron is a potent combination of heme iron, Vitamin B12, and folic acid, designed to address iron deficiency with better absorption and fewer stomach issues. Derived from animal sources, heme iron is absorbed much more efficiently than non-heme iron, making this a preferred choice for those struggling with fatigue or low energy. Each daily dose delivers 10 mg of heme iron, 70 µg folic acid, and 1 µg Vitamin B12 in two soft capsules. It’s a gentle yet effective supplement, ideal for menstruating individuals, vegetarians, or anyone with mild to moderate iron insufficiency. Consumer studies suggest taking iron alongside Vitamin C enhances absorption, so pairing with DHC Vitamin C is a smart move.

• Key ingredients: 10 mg heme iron, 70 µg folic acid, 1 µg Vitamin B12
• Effect: Increases red blood cells, reduces anemia-related fatigue
• Best for: Women, vegetarians, teens, recovering patients
• Who should avoid: Men, postmenopausal women without deficiency, hemochromatosis
• Combine with: DHC Vitamin C to boost uptake

A daily staple, DHC Multivitamin supports overall health by delivering essential vitamins A, B-complex, C, D, and E, making up for nutritional gaps in modern diets. While DHC doesn’t list exact dosages, multivitamins typically contain around 100 % RDA for each vitamin, suitable for daily wellness. This capsule is perfect for anyone seeking balanced health support, from immunity to energy and metabolic health, without taking multiple supplements. It also synergizes well with Perfect Vegetables Premium, offering a nutritious boost when paired.

• Key ingredients: Vitamins A, B1–B12, C, D, E, K
• Effect: Promotes immunity, metabolism, skin, vision, and bone health
• Best for: Those missing nutrients from processed diets, travelers
• Who should avoid: People already on other multivitamins or high-dose vitamins
• Combine with: DHC Perfect Vegetables for enhanced nutrition

DHC Hatomugi Extract is a skin-purifying supplement made from coix seed (commonly known as Job’s tears), a traditional Japanese botanical ingredient long used in Asian medicine. This supplement is designed to improve skin clarity, reduce inflammation, and promote a brighter, more even complexion, making it ideal for people struggling with acne, redness, or dullness. The formula also includes Vitamin E, an antioxidant that helps protect skin from environmental damage and supports healing. Hatomugi’s natural anti-inflammatory properties help calm the skin, while Vitamin E boosts overall resilience. Its benefits are especially noticeable when used consistently alongside other skin-supporting supplements like Vitamin B Complex or Vitamin C.

• Key ingredients: Hatomugi (Job’s tears) extract, Vitamin E, olive oil
• Effect: Calms irritation, evens skin tone, improves hydration
• Best for: Acne-prone skin, sensitive skin, dull or rough texture
• Who should avoid: Individuals with allergies to grains or coix seed
• Combine with: DHC Vitamin B Mix or DHC Vitamin C for enhanced results

DHC Blueberry Extract is specially formulated to protect and improve vision, especially for people who spend long hours in front of screens. It contains bilberry extract, rich in anthocyanins (natural plant pigments with antioxidant benefits), combined with lutein and crocetin, two potent ingredients that support eye function and reduce visual fatigue. In addition to helping with eye strain, this supplement can also support skin health due to its strong antioxidant profile. Lutein and crocetin are known to protect against oxidative stress that leads to aging, both internally and on the skin. If your lifestyle involves high screen time, studying, or digital work, this is one of the most effective DHC supplements to consider.

• Key ingredients: Nordic bilberry extract, lutein, crocetin, carotenoids, B vitamins
• Effect: Reduces eye strain, enhances night vision, improves antioxidant defense
• Best for: Screen users, students, office workers, dry or aging eyes
• Who should avoid: Those with berry or plant pigment allergies
• Combine with: DHC Vitamin C or DHC Omega-3

DHC Plasmalogen is a Japanese-made, soft‑capsule brain-health supplement containing 1,000 µg of plasmalogen (from marine ascidiacea) per daily serving, alongside Lion’s Mane mushroom extract (50 mg) and Sceletium tortuosum (10 mg), designed to support cognitive function, memory, and mental clarity, especially in adults over 40. It uses acid-resistant softcaps to protect the delicate plasmalogen molecules until absorption. Clinical research suggests plasmalogens play a role in cell membrane health, neuroprotection, and may reduce age-related cognitive decline by supporting synaptic function and antioxidant defense. Though larger human trials are needed, recent pilot studies show improved memory and brain signaling after 1 mg/day supplementation in older adults.

• Key ingredients: 1,000 µg marine plasmalogen, 50 mg Lion’s Mane extract, 10 mg Sceletium tortuosum
• Effect: Supports brain cell health, cognitive clarity, stress resilience
• Best for: Adults 40+, mental fog, mild memory concerns
• Who should avoid: Individuals on psychiatric meds, known herb sensitivities
• Combine with: DHC DHA Omega‑3 or Vitamin D for full brain‑body support

DHC Japanese Perfect Vegetables Premium is a powerful DHC food supplement designed to fill the nutritional gap for those who don’t eat enough veggies. Each tablet contains concentrated powders of 32 different Japanese-grown vegetables, including kale, pumpkin, spinach, broccoli, and carrot, along with barley grass, indigestible dextrin, vitamin E, and over 1 trillion lactic acid bacteria and yeast to support stronger digestion and immune health. Taking 2–4 tablets daily (about 2,080–4,160 mg of vegetable powder), this supplement delivers fiber, vitamins, minerals, and probiotics, perfect for those with fast-paced lifestyles or low veggie intake. It is gentle on the stomach, has a mild vegetable aroma, and is safe for long-term use.

• Key ingredients: 32 vegetable powders (kale, broccoli, pumpkin, spinach, etc.), barley grass, Vitamin E, lactic acid bacteria & yeast
• Effect: Fills vegetable nutrient gaps, boosts gut health, adds fiber & antioxidants
• Best for: Busy individuals, picky eaters, poor digestion, low veggie intake
• Who should avoid: People with allergies to soy, milk, yam, or other included vegetables
• Combine with: DHC Multivitamin or DHC Perfect Vegetables for comprehensive nutrient coverage

DHC Natural Vitamin E uses naturally derived d-α-tocopherol, a form of Vitamin E that is more bioavailable than synthetic versions. This supplement helps reduce oxidative stress on skin cells, supports smooth circulation, and promotes skin repair from within, making it a favorite among beauty-conscious users. Vitamin E also plays a key role in maintaining moisture levels in the skin, which helps prevent dryness and premature signs of aging. Its antioxidant power also benefits the cardiovascular system and can enhance skin’s resilience against sun exposure and pollution. For those with dry skin, rough patches, or slow healing, this DHC capsule is a go-to solution.

• Key ingredients: 301.5 mg natural Vitamin E (d-α-tocopherol)
• Effect: Moisturizes skin, enhances blood circulation, slows skin aging
• Best for: Dry skin, fine lines, oxidative stress, poor circulation
• Who should avoid: Individuals taking blood thinners or with vitamin E sensitivity
• Combine with: DHC Multivitamin or benefits of DHC Collagen for anti-aging care

DHC Vitamin D is a simple yet essential supplement that provides 25 µg (1,000 IU) of Vitamin D3 per day, the recommended level for maintaining optimal bone density, calcium absorption, and immune function. This is especially valuable for people who get limited sunlight exposure or live in colder climates where Vitamin D deficiency is common. Beyond bones, Vitamin D supports mood balance and hormone regulation. Some studies suggest it may help improve symptoms of seasonal affective disorder (SAD) and boost mental clarity. As a fat-soluble vitamin, this capsule is best taken with meals or in combination with omega-3 supplements.

• Key ingredients: 25 µg Vitamin D3 (1,000 IU)
• Effect: Strengthens bones, supports calcium absorption, boosts immunity and mood
• Best for: Indoor workers, older adults, people with low sun exposure
• Who should avoid: Those with hypercalcemia or Vitamin D toxicity risk
• Combine with: DHC Calcium & Magnesium or DHA Omega-3

DHC DHA Omega-3 is one of the best-selling DHC food supplements in Japan for maintaining brain, heart, and eye health. Each daily dose provides 510 mg of DHA and 110 mg of EPA, both extracted from high-quality fish oil. These essential fatty acids are crucial for improving memory, concentration, cardiovascular wellness, and even skin elasticity. The supplement is especially beneficial for students, aging adults, or people who don’t consume enough fatty fish in their diet. It’s also a popular choice for those seeking to reduce internal inflammation, something that impacts both health and skin aging. The addition of Vitamin E helps stabilize the oils and adds extra antioxidant support.

• Key ingredients: 510 mg DHA, 110 mg EPA, Vitamin E
• Effect: Enhances brain function, lowers inflammation, supports heart and eye health
• Best for: Older adults, students, low-fish diets, dry skin
• Who should avoid: Those allergic to fish or using anticoagulants
• Combine with: DHC Vitamin D or Multivitamin for full-body wellness

This unique DHC supplement is a herbal formula created to support healthy blood pressure and cardiovascular balance using ingredients like sesame peptides, red yeast rice, GABA, and bitter melon extract. These plant-based compounds are often used in traditional Asian medicine to manage circulatory health and reduce stress-related spikes in blood pressure. While not a replacement for medical treatment, this supplement offers a natural route for mild support. It’s best suited for those looking for preventative heart care or gentle wellness enhancement without relying on prescription medications. Always consult your doctor if you're on blood pressure meds.

• Key ingredients: Sesame peptides, red yeast rice, GABA, bitter melon, sardine peptides
• Effect: Maintains healthy blood pressure, supports circulation, reduces stress
• Best for: Adults with mild blood pressure concerns or family history of hypertension
• Who should avoid: Pregnant women, people on BP medication, those with rice allergies
• Combine with: DHC Omega-3 for heart and vessel synergy

Targeted health concern: Choosing the right DHC supplement starts with identifying your core wellness goals. Whether you're aiming to improve skin, boost immunity, or enhance brain clarity, here are the best pairings:

• For skin elasticity and joint support → pick DHC Collagen
• For immunity and antioxidant protection → choose Vitamin C or Multivitamin
• For brain clarity or cognition → go with DHC Plasmalogen + Omega‑3
• For digestion/fill nutrient gaps → opt for Perfect Vegetables Premium

Lifestyle & dietary fit: Not all formats suit every lifestyle. If convenience or taste is a factor, these suggestions will help match the best DHC supplement to your routine:

• Prefer capsules over powders if you're always on-the-go
• Avoid duplicates (e.g., B-complex + Multivitamin may overlap)

Allergies or sensitivities: Before selecting your supplement, always double-check for allergens. Here’s how to avoid potential issues:

• Fish allergies → skip marine collagen or DHA
• Grain allergies → avoid Hatomugi or Vegetable blends

Health or medication considerations: If you’re managing a health condition or taking prescription medication, these precautions will help you supplement safely:

• On blood thinners → be cautious with fish oil, Vitamin E
• High blood pressure meds → consult before using Atsu Balance

Absorption boosters: To get the most out of your DHC supplements, pair certain nutrients together. Here’s how to maximize absorption and results:

• Pair Vitamin C with Collagen or Iron
• Take minerals like Calcium + Vitamin D together

Whether you're targeting glowing skin, stronger immunity, or daily nutritional support, DHC supplements offer an effective, trusted solution backed by Japanese quality. With minimalist formulas, proven ingredients, and strong global reviews, they’re ideal for modern wellness routines. Ready to upgrade your daily health? Explore our full DHC supplement list at Japan With Love and find your perfect match today!

Before making a purchase, many shoppers have questions about safety, ingredients, and effectiveness. Here are answers to the most common queries about DHC supplements, based on expert sources and customer experience.